MECHANISM OF ACTIVATION OF THE BONE MARROW-DERIVED LYMPHOCYTE
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چکیده
منابع مشابه
Mechanism of Activation of the Bone Marrow-derived Lymphocyte
Peritoneal exudate cells from nu/nu mice stimulated with proteose peptone broth, but in general not from unstimulated mice, permitted cultures of spleen cells from congenitally athymic (nu/nu) mice to respond to the thymus-dependent antigen fowl gamma globulin (FgammaG). Supernatants of cultures of peritoneal cells were also effective, the activity being sensitive to trypsin. Since nu/nu mice w...
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Antigen-induced activation of bone marrow-derived (B) lymphocytes involves interactions between specific antigenic determinants and immunoglobulin receptors on the lymphocyte surface (1). Soluble antigens such as serum proteins can trigger B lymphocytes only if thymus-derived (T) cells are provided (2), thus implying a requirement for some element besides a simple antigen-receptor interaction. ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1973
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.138.6.1466